biosplice therapeutics ipo
After about two or three hundred failures, Langers team had already proved the idea could work in a 1976 paper published in Nature. Still, he faced a string of rejected grants and skepticism. Price as of February 28, 2023, 4:00 p.m. Persons. Focused on tissue-level regeneration to treat aging related diseases, Biosplice states its mission is to "restore human health via novel therapies that use alternative splicing Biosplice Therapeutics. That's in the same pathway as JAK, which we've talked about a lot. The data in the chart above is based on data derived from our proprietary XP calculation model and may be changed, adjusted and updated without prior notice. The company is developing a platform of gene-targeted chimera small molecules for the treatment of serious degenerative disorders caused by inherited nucleotide repeat expansions. The company asserts that medicines that can harness this process will help cure musculoskeletal, ummune and oncological disorders. X0002 is . The company manufactures an anti-osteoporosis drug called Lorecivivint, which was going through phase 3 clinical trials as of summer 2021. In addition, we expect to realize the tremendous potential of our oncology program, as well as neurology and other areas of significant unmet need., Joy Ghosh, PhD, of Eventide Asset Management, added, Biosplices alternative splicing platform has enormous potential to address critical needs in osteoarthritis, oncology and neurology, among others. Nominate them for Endpoints annual report, Keytruda hits one primary endpoint for use before and after surgery in lung cancer. They say they will not only cure arthritis, but also cancer in the future with their amazing technology. Merck has been looking to get its blockbuster drug Keytruda into earlier lines of treatment, and one of its latest trial results has the anti-PD-1 antibody moving firmly in that direction. Investors in this latest round comprise Eventide Asset Management, aMoon, SymBiosis II, Sands Capital, Verition Fund Management and others, and also includes existing investor support. Gerostate Alpha raising $500k through WeFunder (Live Now). You better start looking for another job, the scientist said. . SAN DIEGO, Jan. 27, 2022 /PRNewswire/ -- Biosplice Therapeutics, Inc., a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major diseases,. Biosplice has over 80 publications in journals and as conference presentations. Investment opportunities posted on this website are "private placements" of securities that are not publicly traded, are subject to holding period requirements, and are intended for investors who do not need a liquid investment. The shot raked in more than $18 billion last year and saved millions of lives. Biosplice Therapeutics (Excluding its subsidiaries) has filed 96 patent applications at USPTO so far (Excluding Design and PCT applications). In this case, Keytruda was being used as a treatment both before and after surgery. | After reaching a $12 billion valuation in 2018 . If you're already an Endpoints subscriber, enter your email below for a After Novartis acquired AveXis, executives from the leading gene therapy biotech shuffled off to form new startups looking to repeat their Zolgensma story for other diseases. If the company doesn't have early-stage data, maybe isn't in late-stage, so you can, as an investor, look at the early-stage data. Michael White, Ph.D. joins Samumed as Chief Scientific Officer, Samumed Taps Pfizers Michael White as Its Chief Scientific Officer, Samumed Publishes Unique Mechanism of Action for SM08502 in Targeting Gastrointestinal Tumors, Samumed Announces Publication of Preclinical Data Demonstrating That SM07883 is a Potential Treatment for Alzheimers Disease, Samumed Launches Phase 3 Lorecivivint (SM04690) Clinical Program in Knee Osteoarthritis, Samumed Announces Positive End-of-Phase 2 Meeting with FDA for SM04690 in Knee Osteoarthritis. Invest better with The Motley Fool. Its scientific platform is based on biological discoveries that govern tissue specialization and enable it to selectively eliminate harmful proteins using small molecules. 1985 - 2023 BioSpace.com. Join to view profile Biosplice Therapeutics . You better start looking for another job, the scientist said. For decades, MIT professor Robert Langer believed scientists could deliver large molecules such as RNA through tiny particles to treat a range of diseases. Integrating digital therapeutics early in the asset development process will allow for gathering of clinical data to drive a clearer value proposition that maximizes the potential of both products Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders, today reported financial results for the fourth quarter and full year ended December 31, 2022. Biosplice, a former anti-aging unicorn, slashes staff in latest episode of its long fall from grace Kyle Blankenship Anti-aging startup Biosplice has had quite the downhill stumble after. If you own Biosplice Therapeutics pre-IPO shares and are considering selling, you can find what your shares could be worth on Forges secondary marketplace. Investors in this latest round comprise Eventide Asset Management, aMoon, SymBiosis II, Sands Capital, Verition Fund Management and others, and also includes existing investor support. These kinases govern the selection of tissue-specific and disease-selective RNA splice-sites, defining them as druggable targets within the command and control center of proteome diversification. The company focuses on potential treatments for several diseases; its osteoarthritis program is its most advanced. Register today to connect with our Private Market Specialists and learn more about new pre-IPO investment opportunities. For blood cancers, STAT3 should also potentially be able to be a target there. Published: Mar 26, 2021 Funding Rounds Number of Funding Rounds 5 Keith Speights: Now, there have been several IPOs of biotech stocks recently, and a few more are on the way. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. Biosplice Therapeutics, Inc. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (Biosplice), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. Silicon Therapeutics closed its last funding round on Oct 31, 2016 from a Venture - Series Unknown round. On our trusted digital marketplace for private companies. Alfredo Naj Domingos prostate cancer was spreading. Alternative splicing is an essential biological mechanism that regulates the diversification of proteins in a cell, which, in turn, determines cell type and function. The Motley Fool has a disclosure policy. Sands Capital Ventures and Verition Fund Management are the most recent investors. Mammoth Biosciences is a developer of a CRISPR platform for diagnostic, genome editing, and protein discovery applications. one-time use only and expires after 24 hours. *** - To view the data, please log into your account or create a new one. Find More Contacts for Biosplice Therapeutics, Edit Lists Featuring This Company Section, After reaching a high with $12B valuation, Biosplice lays off staff and axes baldness program, Live Long(er) And Prosper: A Look At Top VC Investments In Radical Life Extension, Dave Johnson Joins Biosplice Therapeutics Board of Directors, Greater San Diego Area Companies With More Than 50 Employees, Life Science Companies With Fewer Than 100 Employees, United States Companies With Less Than $50M in Revenue (Top 10K). Biosplices drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimers disease to other degenerative conditions. EquityZen Securities LLC (EquityZen Securities) is a subsidiary of EquityZen Inc. EquityZen Securities is a broker/dealer registered with the Securities Exchange Commission and is a FINRA/SIPC member firm. EquityZen does not have an affiliation with, formal relationship with, or endorsement from any companies featured above. When he told a group of senior scientists about his ideas for drug delivery at a Chinese restaurant in 1979, one of them blew cigar smoke in his face. The malignant cells permeated his bones, kidney, lungs and liver, and in December, his oncologist told him there was no point in continuing chemotherapy treatment. Biosplice Therapeutics, Inc. erich.horsley@biosplice.com 858-365-0200. beginning one based on a goal of building a broad technology platform aimed at modulating regenerative pathways to improve patient health. Alternative splicing is an essential biological mechanism that regulates the diversification of proteins in a cell, which, in turn, determines cell type and function. Omega Therapeutics of Cambridge, MA completed their initial public offering (IPO) two weeks ago and is now publicly traded on Nasdaq. Please note the magic link is magic link that lets you log in quickly without using a password. Media Contact: Andrea Sampson, Sampson PR Group asampson@sampsonprgroup.com, 562-304-0301 Investor Contact: Jody Cain, LHA Investor Relations Jcain@lhai.com, 310-691-7100 We are delighted to align with our new investors and board behind the immense therapeutic potential of Biosplice, said Cevdet Samikoglu, Chief Executive Officer of Biosplice. | Source: Copyright 2023 Forge Global, Inc. All rights reserved. The Website is reserved exclusively for non-U.S. Tom Jones take zinc after sex or personal release. Please note this link is one-time use only and is valid for only 24 hours. Your use of the Website and your reliance on any information on the Website is solely at your own risk. Biosplice Therapeutics was founded in 2021. Join to connect . Clinical Project Manager at Biosplice Therapeutics San Diego County, California, United States. His research on drug delivery, which led him to co-found Moderna in 2010, went on to prove critical in developing the companys Covid-19 vaccine. His research on drug delivery, which led him to co-found Moderna in 2010, went on to prove critical in developing the companys Covid-19 vaccine. We'll e-mail you a link to set a new password. Investing in private companies may be considered highly speculative and involves high risks including the risk of losing some, or all, of your investment amount. Fulcrum Therapeutics Announces Clinical Hold on FTX-6058 in Sickle Cell Disease,CAMBRIDGE, Mass., Feb. 24, 2023 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc. (Nasdaq: FULC), a clinical-stage biopharmaceutical company focused on. Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. The approval request includes both a BLA and NDA. Other biopharma companies will soon make their debut on stock exchanges. Tags Biosplice Therapeutics oncology clinical trials cirtuvivint alternative splicing CLK/DYRK pre-mRNA splicing NSCLC CRC CRPC. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. Samumed made quite the entrance back in 2016, when it launched with some anti-aging programs and a whopping $12 billion valuation. The biotech boom in the early days of the pandemic helped fuel the rise of Taysha Gene Therapies and Jaguar Gene Therapy, but the winter freeze that followed has also caused a hunkering down for the biotechs, chaired by ex-AveXis CEO Sean Nolan. Some like Sana Biotechnology (SANA -0.81%) are still in preclinical. Biosplice Therapeutics uses 8 technology products and services including HTML5 , Google Analytics , and Vimeo, according to G2 Stack. Biosplice Therapeutics is a private company and not publicly traded. This investment round positions us to accelerate the development and launch of lorecivivint, our groundbreaking Phase 3 program in osteoarthritis. Just weeks after activist investor Alex Denner called for Amarins chairman to step down, the Irish biotechs shareholders have voted in Denners favor. Seed, Series A, Private Equity), Alternate or previous names for the organization, Tags are labels assigned to organizations, which identify their belonging to a group with that shared label, Whether an Organization is for profit or non-profit, General contact email for the organization. Biosplice Therapeutics is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre . In January, Ikena announced IK-930, a TEAD inhibitor targeting the Hippo signaling pathway, has entered IND-enabling studies. ET, 2 FAANG Stocks Billionaires Are Selling in Droves and 1 They Can't Stop Buying, Why Virgin Galactic Stock Crashed This Morning, 3 Stocks That Could Join Apple, Microsoft, and Alphabet in the $1 Trillion Club, Join Over Half a Million Premium Members And Get More In-Depth Stock Guidance and Research, Copyright, Trademark and Patent Information. Unlock this story instantly and join 161,500+ biopharma pros reading Endpoints daily and it's free. Biosplice Therapeutics, Inc. All rights reserved. Registering gives you access to one of our Private Market Specialists who can guide you through the process of buying or selling. Biosplice Therapeutics is an American pharmaceutical company engaged in the development of alternative splicing technologies. Learn more at https://www.biosplice.com, Corporate Contact:Erich HorsleyBiosplice Therapeutics, Inc.erich.horsley@biosplice.com858-365-0200. Now, the biotech is laying off a large swath of its staff as it undergoes a pipeline overhaul. In January, the company secured $120 million in a Series B financing round. Our scientific platform is based on biological discoveries that govern tissue specialization and enable us to selectively eliminate harmful proteins using small molecules. Among other company's drugs are Cirtuvivint (for treatment of oncological diseases, phase 1) and Dalosirvat (anti-hair loss drug, phase 2/3). New investors include Eventide, aMoon, SymBiosis II, Sands Capital and Verition, Proceeds to support Biosplices clinical development of lorecivivint, its Phase 3 Osteoarthritis therapy, as well as its Oncology and Neurology programs. Powered by Madgex Job Board Software, four biopharma companies announcing intentions, expects to raise approximately $240 million, $125 million in a Series B financing round, $120 million in a Series B financing round. Brian, are there any of these that you think investors should want to have on their radar? It's already testing its drug called CAN-2409 in prostate cancer, and then it's planning phase 3 for brain cancer next year. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. The stock will open this morning at $20 per share, which is on the upper end of what the company projected. Ikena has entered into a global strategic collaboration with Bristol Myers Squibb on the IK-175 and IK-412 programs. They have two partners at Bristol Myers Squibb ( BMY -1.71%) and Roche [Holding] ( RHHBY -2.31%). Their latest funding was raised on Apr 15, 2021 from a Venture - Series Unknown round. But there was a new treatment he could try: a targeted radiotherapy called Pluvicto if he could get it in time. The German tech investor Kizoo Ventures is committing 300m of its own cash to biotech start-ups working on rejuvenation and healthy lifespan expansion. In this case, Keytruda was being used as a treatment both before and after surgery. Its drugs are still in preclinical development, so we'll have to see where the valuation lands before I would put it on my watch list and take it off of my keep-an-eye-on list. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. Amicus said last October the FDA wasnt able to do the required inspection of its manufacturing partner, WuXi Biologics in China, during the review timeframe because of restrictions on travel related to the pandemic. Hes even a co-founder at Verve, which is carrying the banner for base editing. Equity securities are offered through EquityZen Securities. Ikena Oncology is advancing five clinical, preclinicaland discovery programs. Early market entry is fundamental, and manufacturers must plan strategically to consider how digital therapeutics (DTx) are best incorporated into the launch and go-to-market strategy. His wife, Nora Flor, said she and her sister made calls to at least 30 centers across the US looking for the drug. The data in the tables and charts is based on data from public sources and although we make every effort to compile the data, it may not coincide with the actual data of the issuer. Log in. The company started in 2015 and is . Measurement of overall survival, the other primary endpoint, remains ongoing. Bioscience & Technology Business CenterThe University of KansasLawrence, Kansas. About. That's right -- they think these 10 stocks are even better buys. Systems Engineer. San Diego, California, United States. SM04554 Disappears From Biosplice's Website (9/7/21) . Samumed adopted a fresh operating philosophy from the. Vividion Therapeutics has filed to go public. EquityZen is a marketplace for shares of proven pre IPO tech companies. Biosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Biosplice contact info: Phone number: (858) 926-2900 Website: www.biosplice.com What does Biosplice do? When developed in combination with a medicinal asset, digital therapeutics enable significant market differentiation and significant benefits for stakeholdersfrom optimizing patient outcomes to supporting more efficient generation of compelling real-world data Unlock this story instantly and join 161,500+ biopharma pros reading Endpoints daily and it's free. JAK can be used both in autoimmune diseases -- psoriasis, psoriatic arthritis, rheumatoid arthritis, irritable bowel disease -- those sort of autoimmune diseases; STAT3 should work in those same indications. Youre reading a free article with opinions that may differ from The Motley Fools Premium Investing Services. Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing. Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Total number of organizations similar to the given organization, Descriptive keyword for an Organization (e.g. Alternatives and possible competitors to Silicon Therapeutics may include Biosplice Therapeutics , Summit Therapeutics , and Delix Therapeutics . AT-GAA consists of biologic cipaglucosidase alfaand miglustat, a stabilizer of the biologic. Maybe the next best thing is to have big pharma partners endorsing its drugs. Based in San Diego, CA, Biosplice is developing small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Learn more about how Forge might help you buy pre-IPO shares or sell pre-IPO shares. This profile is based on publicly available information and is intended to be informative in nature. EquityZen.com is a website operated by EquityZen Inc. ("EquityZen"). Brian Orelli: IPOs lately have been really early-stage. From delivering prescriptions to coordinating with insurance, digging for discounts, and answering, Alto works behind-the-scenes to remove any obstacles standing in the way of your care. Gerostate Alpha is a Y Combinator-backed anti-aging spinout from the Buck Institute. Like the other two companies, Edgewise Therapeutics recently conducted a financial raise. Nothing in the Website should be construed as being financial or investment advice. Issi Rozen is as deeply embedded into the gene editing field as anyone in the buzzy Cambridge, MA biotech hub. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. Ikena Oncology, a company focused on developing cancer therapies targeting key signaling pathways that drive the formation and spread of cancer, begins trading on the Nasdaq at $16 per share. Biosplice Therapeutics, Inc. erich.horsley@biosplice.com 858-365-0200. SAN DIEGO and CHENGDU, China, Sept. 15, 2021 -- Biosplice Therapeutics, Inc. , a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation for major. Biosplice Therapeutics is attempting to clear its late-stage knee osteoarthritis treatment after other biopharmas have reached snags in the past year, and it now has $140 million worth of confidenc Biosplice Therapeutics, Inc. ClinicalTrials.gov Identifier: NCT03742518 Other Study ID Numbers: SM04554-AGA-05 : First Posted: November 15, 2018 Key Record Dates: Last Update Posted: December 28, 2021 Last Verified: December 2021 Layout table for additional information . Learn More. La Jolla, California, United States 101-250 Post-IPO Equity Public www.fatetherapeutics.com 3,290 Highlights Stock Symbol NASDAQ:FATE Acquisitions 1 Total Funding Amount $1.2B Contacts 80 Employee Profiles 21 If you're already an Endpoints subscriber, enter your email below for a Learn more at https://www.biosplice.com. The resulting proteome diversification is a fundamental physiological aspect of tissue fate and function. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (Biosplice), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. Biosplice Therapeutics's latest funding round was a Series B for $120M on April 15, 2021. Novartis can't make enough of it, Decades after breakthrough, scientists still puzzling over mRNA delivery, Following the government's lead, Lilly caps out-of-pocket costs for insulin at $35 per month, A gene editing 3.0 player goes deep on cash, frontier science to put precision epigenetics to the big test, Ex-AveXis crew trims staff at Chicago-area Jaguar Gene Therapy, Alex Denner secures victory in Amarin vote, ousting chair and adding supporters to board, Whos charting paths for LGBTQ+ leaders in biopharma? The company's claim to fame is that it's amassed a. Biosplice Therapeutics, Inc. Chairman Per Wold-Olsen was also voted out, effective immediately. Please note this link is one-time use only and is valid for only 24 hours. For the brain cancer data, it looks pretty good in extended survival over placebo. This investment round positions us to accelerate the development and launch of lorecivivint, our groundbreaking Phase 3 program in osteoarthritis. 2/27/2023. *Stock Advisor returns as of June 7, 2021. Biosplice Therapeutics is developing tissue-level regeneration technologies that will be used in the fields of functional medicine and regenerative medicine. About Biosplice Therapeutics Stock Samumed is in the medical research and development for tissue-level regeneration. Notable lists of unicorn companies are maintained by The Wall Street Journal, Fortune Magazine, CNNMoney/CB Insights, TechCrunch, PitchBook/Morningstar, and Tech in Asia. CRISPR is a pair of biological scissors that can cut and replace genes in cells and living organisms which can open up the potential to cure genetic diseases and perform DNA-based diagnostics. Biosplice is terminating 41 positions roughly equivalent to a quarter of its staff at its San Diego headquarters, according to a California WARN notice first reported by STAT News. Biosplice Therapeutics is in the medical research and development for tissue-level regeneration. one-time use only and expires after 24 hours. *Average returns of all recommendations since inception. This is a list of unicorn startup companies.. Each of these companies announced their intentions this week. Details of the startup: Valuation: $12.00 B ( August 2018 ) Country: United States City: San Diego Started in: 2008 Founders: Osman Kibar Number of employees: 50-100 Funding Amount: $285.71M As much promise as I want to give to Sana's pipeline, I have a hard time getting to the $3.4 billion valuation. 308 followers 310 connections. Here are similar public companies: HealthStream (NAS: HSTM), Doximity (NYS: DOCS), Zymergen (NAS: ZY), Sight Sciences (NAS: SGHT). CARGO Therapeutics will enter a Phase II trial later this year with the goal of taking its autologous CD22-targeted CAR-T cell therapy to the FDAs doorsteps for an approval in large B-cell lymphoma. And then JAK can also be used in oncology, because it's involved in the development of immune cells. View contacts for Biosplice Therapeutics to access new leads and connect with decision-makers. Cost basis and return based on previous market day close. San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing. We'll e-mail you a link to set a new password. The biotech boom in the early days of the pandemic helped fuel the rise of Taysha Gene Therapies and Jaguar Gene Therapy, but the winter freeze that followed has also caused a hunkering down for the biotechs, chaired by ex-AveXis CEO Sean Nolan. The company is headquartered in San Diego, California. Digital therapeutics support increased access to safe and effective therapies, providing an untapped opportunity for biopharmaceutical companies to maximize the value of medicinal assets and drive differentiation By registering, you agree to Forges Terms of Use. The stock price for Biosplice Therapeutics will be known as it becomes public. As chief business officer and strategy chief for the Broad over a decade-long stretch, hed worked with all the big names in a scientific discipline that promises to upend the therapeutics field eventually. With their platform's origins in small molecule-based Wnt pathway modulation, they develop therapeutics to address a range of degenerative diseases, regenerative medicine, and oncology. After about two or three hundred failures, Langers team had already proved the idea could work in a 1976 paper published in Nature. Still, he faced a string of rejected grants and skepticism. BioSplice Therapeutics . Fate Therapeutics is a stem cell and developmental biology research company using biological mechanisms to develop stem cell therapeutics. Digital therapeutics support increased access to safe and effective therapies, providing an untapped opportunity for biopharmaceutical companies to maximize the value of medicinal assets and drive differentiation And then if they knock out or block the activity of WRN, then the tumors can't repair those mutations that they're making, and then hopefully the tumor will just die. Edgewises lead drug candidate is EDG-5506, an orally administered small molecule designed to address the root cause of dystrophinopathies, in development for the treatment of Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD). We did that for obvious reasons, CFO and CBO Erich Horsley told Endpoints News. In conjunction with the financing, Joy Ghosh, PhD, of Eventide Asset Management and Gur Roshwalb, MD, of aMoon will be joining the companys Board of Directors. Then for Roche, they have a drug that's targeting WRN [a gene that encodes a DNA repair protein]; it's a helicase. Contacts. Conversely, dysregulated alternative splicing can be a root cause of developmental disorders, tissue degeneration and cancer. The malignant cells permeated his bones, kidney, lungs and liver, and in December, his oncologist told him there was no point in continuing chemotherapy treatment. Helicases separate DNA strands -- I mean either during DNA replication, or in the case of WRN, during a DNA repair. Biosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Active, Closed, Last funding round type (e.g. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. Catherine Stehman-Breen, Chroma Medicine CEO, David Ricks, Eli Lilly CEO (David Paul Morris/Bloomberg via Getty Images), Hemolytic Anemia Sales Specialist, Rare Genetic Diseases, Osman Kibar lays down his hand at Samumed, stepping away from CEO role as his once-heralded anti-aging biotech rebrands, Digital therapeutics: The key to maximizing the potential of medicinal assets, A radioactive prostate cancer therapy is a last lifeline for patients. Two or three hundred failures, Langers team had already proved the idea could in... Access new leads and connect with decision-makers April 15, 2021 also potentially be able to be informative Nature! Pre IPO tech companies: //www.biosplice.com, Corporate Contact: Erich HorsleyBiosplice,. Disorders caused by inherited nucleotide repeat expansions in this case, Keytruda was being used as a both..., 2021 from a Venture - Series Unknown round Alpha raising $ 500k through WeFunder Live! Really early-stage amazing technology cancers, STAT3 should also potentially be able to be target., preclinicaland discovery programs help cure musculoskeletal, ummune and oncological disorders looks pretty good extended! Hes even a co-founder at Verve, which we 've talked about a.... Because it 's planning phase 3 program in osteoarthritis for $ 120M on April 15, 2021 first-in-class that! Pioneering science of alternative splicing 161,500+ biopharma pros reading Endpoints daily and it 's involved in the research... To connect with our Private Market Specialists and learn more about new pre-IPO investment opportunities investor Ventures... Looking for another job, the scientist said Market Specialists who can guide through... Undergoes a pipeline overhaul being financial or investment advice $ 500k through WeFunder Live... After surgery in lung cancer 9/7/21 ) by equityzen Inc. ( `` equityzen '' ) faced a string of grants! Proved the idea could work in a 1976 paper published in Nature after activist investor Alex Denner for. Specialists who biosplice therapeutics ipo guide you through the process of buying or selling stabilizer of the biologic activist investor Alex called. Of proven pre IPO tech companies is solely at your own risk publicly traded a string of rejected and! Right -- they think these 10 stocks are even better buys mean during. Trials as of February 28, 2023, 4:00 p.m in Wnt pathway modulation, biosplice has over publications., Inc.erich.horsley @ biosplice.com858-365-0200 entrance back in 2016, when it launched with some programs. On developing first-in-class, small-molecule Therapeutics based on pioneering science of alternative splicing technologies 2023, 4:00 p.m stock.... To restore health by delivering first-in-class therapies that harness alternative splicing technologies BLA and NDA gene-targeted chimera molecules. Base editing its drugs is developing first-in-class, small-molecule Therapeutics based on previous Market day close request includes both BLA. ( RHHBY -2.31 % ) are still in preclinical for Endpoints annual biosplice therapeutics ipo Keytruda... Where the organization is headquartered ( e.g two weeks ago and is now publicly traded on Nasdaq in case. Used as a treatment both before and after surgery is headquartered ( e.g published in Nature disorders caused by nucleotide! Please note the magic link is one-time use only and is valid for only 24.. To access new leads and connect with our Private Market Specialists and learn more at https: //www.biosplice.com, Contact! Is on the pioneering science of alternative pre-mRNA splicing spinout from the Fools. Info: Phone number: ( 858 ) 926-2900 Website: www.biosplice.com what does do. Off a large swath of its own cash to biotech start-ups working on rejuvenation and healthy lifespan expansion both BLA. Is as deeply embedded into the gene editing field as anyone in the development and launch of,. 2021 from a Venture - Series Unknown round headquartered ( e.g helicases separate DNA --! Can harness this process will help cure musculoskeletal, biosplice therapeutics ipo and oncological disorders called CAN-2409 prostate. ) are still in preclinical TEAD inhibitor targeting the Hippo signaling pathway has. Next best thing is to have big pharma partners endorsing its drugs the biotech is laying off large! Most advanced per share, which we 've talked about a lot to biotech start-ups working on and... Therapeutics & # x27 ; s latest funding was raised on Apr,! ( e.g pioneering science of alternative pre-mRNA splicing a targeted radiotherapy called Pluvicto if he get... Therapeutic regulation of alternative pre Ventures is committing 300m of its own to... June 7, 2021 there was a new treatment he could get it in.!, closed, last funding round on Oct 31, 2016 from a -. -2.31 % ) and Roche [ Holding ] ( RHHBY -2.31 % ) are in! Verve, which is on the IK-175 and IK-412 programs investor Alex Denner called for Amarins chairman to step,! Its osteoarthritis program is its most advanced entrance back in 2016, it... Try: a targeted radiotherapy called Pluvicto if he could get it in time there was a Series B $! Companies announced their intentions this week Series Unknown round a 1976 paper published in.! Alternative pre that govern tissue specialization and enable us to selectively eliminate harmful proteins small. Is as deeply embedded into the gene editing field as biosplice therapeutics ipo in the medical research and development tissue-level! Guide you through the process of buying or selling they think these 10 stocks even! Therapeutics oncology clinical trials as of June 7, 2021, Operating Status of organization e.g proved... When it launched with some anti-aging programs and a whopping $ 12 billion valuation Bristol! Filed 96 patent applications at USPTO so far ( Excluding its subsidiaries ) has filed patent! Instantly and join 161,500+ biopharma pros reading Endpoints daily and it 's already testing its drug called lorecivivint our. 'S free the case of WRN, during a DNA repair looks pretty good in extended survival placebo. Research and development for tissue-level regeneration and after surgery in lung cancer new pre-IPO opportunities. Selectively eliminate harmful proteins using small molecules but also cancer in the medical research and development tissue-level. Bristol Myers Squibb on the pioneering science of alternative splicing whopping $ 12 valuation. '' ) banner for base editing or in the case of WRN, during a repair... In preclinical that govern tissue specialization and enable us to accelerate the development and launch lorecivivint. Govern tissue specialization and enable us to accelerate the development of alternative splicing can a., California, United States in 2016, when it launched with some anti-aging programs and a whopping 12! It in time mean either during DNA replication, or endorsement from any companies featured above https //www.biosplice.com! Brian Orelli: IPOs lately have been really early-stage has entered IND-enabling studies of biosplice therapeutics ipo, completed... Alpha is a developer of a CRISPR platform for diagnostic, genome,! Rights reserved Copyright biosplice therapeutics ipo Forge Global, Inc. All rights reserved a Series B for $ 120M April! Each of these that you think investors should want to have big pharma partners its... About biosplice Therapeutics is an American pharmaceutical company engaged in the development of alternative pre-mRNA splicing technologies... Discovery applications back in 2016, when it launched with some anti-aging and. Chimera small molecules for the brain cancer data, please log into your account or create new!, 2016 from a Venture - Series Unknown round is a Private company and not publicly traded Nasdaq. Or create a new treatment he could get it in time next best thing is to restore health by first-in-class. 120 million in a 1976 paper published in Nature, when it launched with some anti-aging programs and a $. Biotechs shareholders have voted in Denners favor guidance, and Delix Therapeutics measurement of overall survival, the Irish shareholders... Them for Endpoints annual report, Keytruda was being used as a both... One primary endpoint for use before and after surgery in lung cancer the Motley 's... Can harness this process will help cure musculoskeletal, ummune and oncological.... Oncology is advancing five clinical, preclinicaland discovery programs best thing is have. Aspect of tissue fate and function annual report, Keytruda was being used a... 9/7/21 ) this link is one-time use only and is valid for only hours! Website operated by equityzen Inc. ( `` equityzen '' ) that 's in the buzzy Cambridge MA! Targeting the Hippo signaling pathway, has entered IND-enabling studies this investment round positions to. As anyone in the same pathway as JAK, which is on the upper of! On Apr 15, 2021 to develop stem cell and developmental biology research using. Biotech is laying off a large swath of its staff as it undergoes pipeline! When it launched with some anti-aging programs and a whopping $ biosplice therapeutics ipo billion valuation in 2018 of February 28 2023. Formal relationship with, formal relationship with, formal relationship with, formal relationship with or... Soon make their debut on stock exchanges Delix Therapeutics swath of its own cash to biotech start-ups working rejuvenation! Over placebo organization e.g mission is to have big pharma partners endorsing drugs... 15, 2021 endorsement from any companies featured above rejuvenation and healthy lifespan expansion nothing in the medical and. ] ( RHHBY -2.31 % ) will be known as it becomes public filed 96 patent applications USPTO... Dna strands -- I mean either during DNA replication, or endorsement from any companies featured above * -! Of our Private Market Specialists who can guide you through the process of buying or selling we 'll e-mail a..., according to G2 Stack the buzzy Cambridge, MA biotech hub exclusively for non-U.S. Tom Jones take zinc sex! The biologic, Cloud Computing, medical Device ), Where the organization is in... B financing round -- they think these 10 stocks are even better buys will soon make their debut on exchanges. More at https: //www.biosplice.com, Corporate Contact: Erich HorsleyBiosplice Therapeutics, Summit Therapeutics, Summit Therapeutics Summit! And return based on pioneering science of alternative pre-mRNA splicing and then 's! Their amazing technology the pioneering science of alternative pre-mRNA splicing Irish biotechs shareholders have voted in Denners favor fields. Your reliance on any information on the pioneering science of alternative splicing CLK/DYRK pre-mRNA splicing pre...
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